Table 3:
Random-Effects Logistic Regression Model Showing the Relationship between Statin and Free of Delirium, Adjusted by CRP
Statin + CRP: Free of Delirium |
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(n = 225; Person-Days = 1,117) |
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OR | 95% CI | P Value | |
Statin | 1.56 | 0.64–3.79 | 0.32 |
CRP | 0.68 | 0.51–0.90 | 0.01 |
Age, per year | 0.99 | 0.96–1.02 | 0.46 |
Sex, women vs. men | 0.62 | 0.25–1.53 | 0.30 |
mSOFA, per point | 0.60 | 0.48–0.76 | <0.01 |
Sepsis, yes vs. no | 2.46 | 0.95–6.36 | 0.06 |
Propensity score* | 3.63 | 0.41–31.8 | 0.24 |
Ventilated, yes vs. no | 0.74 | 0.68–0.81 | <0.01 |
Elective vs. emergency | 17.6 | 3.96–78.1 | <0.01 |
Definition of abbreviations: CI = confidence intervals; CRP = C-reactive protein; mSOFA = Sequential Organ Failure Assessment (minus Glasgow Coma Score); OR = odds ratio.
CRP quantities log(e) transformed to obtain normal distribution. When used as a dependent variable, OR is per increase in standard deviation of log(e) CRP.
All models allow for random-effects for each individual.
Propensity score according to age, sex, primary hypercholesterolemia, ischemic heart disease, diabetes, peripheral and cerebrovascular disease, and admission for aortic aneurysm surgery.