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. 2014 Mar 15;189(6):666–673. doi: 10.1164/rccm.201306-1150OC

Table 3:

Random-Effects Logistic Regression Model Showing the Relationship between Statin and Free of Delirium, Adjusted by CRP

  Statin + CRP: Free of Delirium
  (n = 225; Person-Days = 1,117)
  OR 95% CI P Value
Statin 1.56 0.64–3.79 0.32
CRP 0.68 0.51–0.90 0.01
Age, per year 0.99 0.96–1.02 0.46
Sex, women vs. men 0.62 0.25–1.53 0.30
mSOFA, per point 0.60 0.48–0.76 <0.01
Sepsis, yes vs. no 2.46 0.95–6.36 0.06
Propensity score* 3.63 0.41–31.8 0.24
Ventilated, yes vs. no 0.74 0.68–0.81 <0.01
Elective vs. emergency 17.6 3.96–78.1 <0.01

Definition of abbreviations: CI = confidence intervals; CRP = C-reactive protein; mSOFA = Sequential Organ Failure Assessment (minus Glasgow Coma Score); OR = odds ratio.

CRP quantities log(e) transformed to obtain normal distribution. When used as a dependent variable, OR is per increase in standard deviation of log(e) CRP.

All models allow for random-effects for each individual.

*

Propensity score according to age, sex, primary hypercholesterolemia, ischemic heart disease, diabetes, peripheral and cerebrovascular disease, and admission for aortic aneurysm surgery.