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. Author manuscript; available in PMC: 2014 Apr 3.
Published in final edited form as: Twin Res Hum Genet. 2013 Apr;16(2):525–534. doi: 10.1017/thg.2013.11

TABLE 4.

Results of Bivariate Model-Fitting of Disordered Gambling and Alcohol Use Disorder

Alcohol use disorder phenotype Proportion of variation
Correlations between factors explaining variation in risk for disordered gambling and alcohol use disorder
Additive genetic Unique environment Genetic correlations Environmental correlations
Full sample
DSM-IV alcohol dependencea 0.48 (0.35, 0.61) 0.52 (0.39, 0.65) 0.44 (0.33, 0.49) 0.32 (0.13, 0.42)
DSM-5 alcohol use disordera 0.50 (0.42, 0.57) 0.51 (0.43, 0.58) 0.29 (0.16, 0.36) 0.37 (0.28, 0.42)
DSM-IV AUD symptom countb 0.43 (0.38, 0.48) 0.57 (0.52, 0.62) 0.35 (0.32, 0.38) 0.22 (0.17, 0.27)
Men
DSM-IV alcohol dependencea 0.41 (0.22, 0.61) 0.58 (0.39, 0.78) 0.46 (0.31, 0.52) 0.35 (0.08, 0.45)
DSM-5 alcohol use disordera 0.52 (0.40, 0.65) 0.48 (0.37, 0.59) 0.30 (0.08, 0.39) 0.42 (0.32, 0.46)
DSM-IV AUD symptom countb 0.49c (0.41, 0.56) 0.51 (0.44, 0.59) 0.41d (0.38, 0.43) 0.25 (0.17, 0.31)
Women
DSM-IV alcohol dependencea 0.54 (0.36, 0.72) 0.46 (0.28, 0.64) 0.39 (0.16, 0.48) 0.25 (−0.18, 0.40)
DSM-5 alcohol use disordera 0.47 (0.35, 0.58) 0.54 (0.43, 0.65) 0.28 (0.04, 0.37) 0.27 (0.01, 0.37)
DSM-IV AUD symptom countb 0.38c (0.31, 0.44) 0.66 (0.56, 0.69) 0.29d (0.24, 0.34) 0.20 (0.11, 0.26)

Note:

a

Using categorical 1+ symptom phenotype of disordered gambling;

b

using continuous disordered gambling phenotype, 95% confidence intervals are in parentheses.

c

Parameter estimate differed for men and women, Δχ2 = 8.72, df = 1, p = .003.

d

Parameter estimate differed for men and women, Δχ2 = 13.82, df = 1, p = .0002.