Figure 2. ArcA and Fnr ubiquitously regulate the three branches of metabolism.

Transcription factor regulated gene products are shown in terms of their biological context in the metabolic network. The principal dimensions of metabolism are shown as two large arrows for the formation of biomass or energy. All of the 12 biomass precursors (10/12 regulated) and 9 primary electron donors (9/9 regulated) are shown with arrows flowing into biomass formation or chemiosmosis. The anabolic process is pictorialized with the number of genes regulated in each of the biosynthetic pathways and the chemiosmotic process is shown primarily via the electron transport chain. Numbers indicate the number of regulated genes upstream or downstream of key precursors (e.g. 19 genes encoding reactions for transport and secondary catabolism pathways are regulated upstream of pyruvate).