Table 1. Count of GCR events with and without duplication of the left arm of chromosome V from the uGCR assay.
Genotype | Isolates analyzed * | With ChrV L duplication | Without ChrV L duplication | ||||
total | hph+ | hph− | total | hph+ | hph− | ||
Wild-type | 27 | 1 | 1 | 0 | 26 | 1 | 25 |
tel1 | 31 | 14 | 10 | 4 | 17 | 8 | 9 |
tel1 lig4 | 58 | 27 | 17 | 10 | 31 | 1 | 30 |
tel1 rad52 | 34 | 0 | 0 | 0 | 34 | 5 | 29 |
sae2 | 28 | 21 | 14 | 7 | 7 | 0 | 7 |
tel1 sae2 | 22 | 11 | 5 | 6 | 11 | 1 | 10 |
exo1 sae2 | 20 | 5 | 3 | 2 | 15 | 1 | 14 |
mre11 | 21 | 1 | 1 | 0 | 20 | 1 | 19 |
mre11-3 ** | 6 | 0 | 0 | 0 | 6 | 3 | 3 |
mre11-H125N ** | 7 | 0 | 0 | 0 | 7 | 3 | 4 |
* The presence of a duplication of the left arm of chromosome V was determined by WGS, aCGH, and/or MLPA.
** The mre11-3 and mre11-H125N alleles were present on plasmids in a strain with a chromosomal deletion of MRE11.