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. 2014 Apr 3;9(4):e91742. doi: 10.1371/journal.pone.0091742

Figure 1. Expression of MECP2 isoforms in SK-N-SH cells stably infected with recombinant lentiviruses.

Figure 1

A) Infection with the MECP2_e1 vector increases MECP2_e1 mRNA level ∼35-fold, compared with the brain frontal cortex and ∼100-fold compared with the eGFP control infected cells. Infection with the MECP2_e2 vector increases MECP2_e2 mRNA level 11-fold compared with the brain frontal cortex and the eGFP control. Relative quantities of MECP2_e1 and MECP2_e2 transcripts for each treatment/sample are indicated in data labels, below sample names; B) In cells infected with the MECP2_e1 vector, MECP2_e1 transcript is ∼5 times more abundant than the MECP2_e2 transcript. In cells infected with the MECP2_e2 vector, the MECP2_e2 transcript is ∼100 times more abundant than the MECP2_e1 transcript. In cells infected with the eGFP control and in the brain frontal cortex, the MECP2_e2 transcript is ∼9 times more abundant than the MECP2_e1 transcript.