Table 5. Comparison of methods analyzing CNV using FFPE tissue.
Thompson et al | Little et al | Tuefferd et al | Lips et al | Oosting et al | Soroush et al | Yu et al | |
Platform | Affymetrix | GenomePlex | Affymetrix | Illumina | Illumina/Affymetrix | Agilent/Affymetrix | Affymetrix |
Array Type | 10K | aCGH | SNP 6.0 | BeadArray | BeadArray/10K | aCGH/SNP6.0 | CytoscanHD |
Number of Loci | 10000 | 5623 | 1.85 million | 5861 | 5861/10000 | 40161/1.85 million | 2.6 million |
CNV FFPE vs. Frozen | NE | NE | 53% | NA | NE | NA | 93.80% |
CNV FFPE vs. karyotype | NE | NE | NE | NA | NE | NA | 91% |
FISH validation rate | NE | NE | NE | NA | NE | NA | 93.80% |
NE-Not examined; NA-Not applicable.