Table 1. The Expression of UPK1A and the Clinicopathologic Characteristics of Patients with Gastric Cancer.
Characteristics | number | UPK1A Expression (%) | |||
Low | High | χ2 | p Value | ||
Gender | 0.499 | 0.48 | |||
Male | 301 | 155 | 146 | ||
Female | 144 | 69 | 75 | ||
Location | 5.483 | 0.14 | |||
Fundus of stomach | 181 | 81 | 100 | ||
Proximal | 67 | 36 | 31 | ||
Distant | 173 | 91 | 82 | ||
Total | 24 | 16 | 8 | ||
Histological grade | 7.598 | 0.022a | |||
Well differentiated (G1) | 285 | 151 | 134 | ||
Moderately differentiated (G2) | 73 | 26 | 47 | ||
Poorly differentiated (G3) | 87 | 47 | 40 | ||
Radical resection | 0.518 | 0.472 | |||
Yes | 375 | 186 | 189 | ||
No | 70 | 38 | 32 | ||
Tumor emboli in vasculature | 1.497 | 0.221 | |||
No | 401 | 198 | 203 | ||
Yes | 44 | 26 | 18 | ||
Tumor invasion (T) | 5.285 | 0.259 | |||
T1 | 33 | 11 | 22 | ||
T2 | 42 | 20 | 22 | ||
T3 | 82 | 40 | 42 | ||
T4a | 239 | 125 | 114 | ||
T4b | 49 | 28 | 21 | ||
Nodal status (N) | 19.104 | <0.001a | |||
N0 | 122 | 43 | 79 | ||
N1 | 86 | 41 | 45 | ||
N2 | 103 | 58 | 45 | ||
N3 | 134 | 82 | 52 | ||
Metastasis status (M) | 0.008 | 0.928 | |||
M1 | 390 | 196 | 194 | ||
M2 | 55 | 28 | 27 | ||
TNM staging 7th ed | 11.96 | 0.008a | |||
Stage I | 46 | 15 | 31 | ||
Stage II | 104 | 45 | 59 | ||
Stage III | 239 | 136 | 103 | ||
Stage IV | 56 | 28 | 28 |
pN, pathological node; pT, pathological tumor; pTNM, pathological tumor/node/metastasis; UPK1A, Uroplakin 1A.
Statistically significant (p<0.05).