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. 2014 Apr 3;9(4):e93073. doi: 10.1371/journal.pone.0093073

Table 1. The Expression of UPK1A and the Clinicopathologic Characteristics of Patients with Gastric Cancer.

Characteristics number UPK1A Expression (%)
Low High χ2 p Value
Gender 0.499 0.48
Male 301 155 146
Female 144 69 75
Location 5.483 0.14
Fundus of stomach 181 81 100
Proximal 67 36 31
Distant 173 91 82
Total 24 16 8
Histological grade 7.598 0.022a
Well differentiated (G1) 285 151 134
Moderately differentiated (G2) 73 26 47
Poorly differentiated (G3) 87 47 40
Radical resection 0.518 0.472
Yes 375 186 189
No 70 38 32
Tumor emboli in vasculature 1.497 0.221
No 401 198 203
Yes 44 26 18
Tumor invasion (T) 5.285 0.259
T1 33 11 22
T2 42 20 22
T3 82 40 42
T4a 239 125 114
T4b 49 28 21
Nodal status (N) 19.104 <0.001a
N0 122 43 79
N1 86 41 45
N2 103 58 45
N3 134 82 52
Metastasis status (M) 0.008 0.928
M1 390 196 194
M2 55 28 27
TNM staging 7th ed 11.96 0.008a
Stage I 46 15 31
Stage II 104 45 59
Stage III 239 136 103
Stage IV 56 28 28

pN, pathological node; pT, pathological tumor; pTNM, pathological tumor/node/metastasis; UPK1A, Uroplakin 1A.

a

Statistically significant (p<0.05).