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. Author manuscript; available in PMC: 2014 Aug 1.

Published in final edited form as: Eur J Endocrinol. 2014 Mar 13;170(4):645–650. doi: 10.1530/EJE-13-0862

Table 1.

Characteristics of 314 subjects at baseline by gender and treatment group ± S.D.

	Men			Women
	Placebo	Calcium+D	P	Placebo	Calcium+D	P
N	67	66		95	86
Age, yrs	71.2 ± 5.1	70.6 ± 4.5	0.475	71.9 ± 4.6	70.9 ± 4.3	0.143
Body Mass Index, kg/m²	27.0 ± 3.2	26.9 ± 3.0	0.760	26.5 ± 4.7	26.3 ± 3.9	0.742
PASE score	125.9 ± 56.9 (66)	132.3 ± 56.6 (65)	0.519	108.5 ± 53.0	104.8 ± 45.9	0.535
Calcium intake, mg/d	700.6 ± 382.0	750.0 ± 411.1	0.474	801.0 ± 349.0	678.1 ± 281.4	0.010
eGFR, ml/min/1.73m²	74.8 ± 14.8	79.9 ± 15.1	0.050	73.8 ± 11.9	76.3 ± 14.1	0.202
*Serum measures*
Sclerostin, ng/ml	28.9 ± 11.4	31.3 ± 23.2	0.450	27.8 ± 14.1	28.5 ± 14.5	0.726
25-hydroxyvitamin D, nmol/L	88.9 ± 30.0	84.9 ± 40.8	0.516	63.3 ± 7.5	73.3 ± 33.7	0.030
Total calcium, ng/L	2.51 ± 0.07 (66)	2.51 ± 0.08	0.526	2.52 ± 0.08	2.55 ± 0.07	0.034
Parathyroid hormone, pmol/L	3.61 ± 1.37	4.09 ± 2.06	0.122	4.45 ± 1.96	3.88 ± 1.40	0.027
Osteocalcin, nmol/L	1.01 ± 0.34	0.93 ± 0.23	0.131	1.25 ± 0.41	1.19 ± 0.38	0.309
Estradiol, pmol/L	99.4 ± 38.8 (63)	106.5 ± 44.5 (64)	0.336	93.0 ± 54.1 (90)	94.4 ± 68.0 (83)	0.878
Testosterone, nmol/L	16.6 ± 4.8 (62)	17.5 ± 4.8 (63)	0.302	1.3 ± 0.9 (89)	1.4 ± 1.1 (83)	0.782
*BMD measures*
Femoral neck BMD, g/cm²	0.94 ± 0.11	0.98 ± 0.14	0.033	0.80 ± 0.10	0.80 ± 0.11	0.609
L2-4 BMD, g/cm²	1.26 ± 0.19 (66)	1.33 ± 0.20 (65)	0.053	1.03 ± 0.20 (91)	1.03 ± 0.19 (79)	0.913
Total body BMD, g/cm²	1.19 ± 0.08 (66)	1.21 ± 0.09	0.159	1.01 ± 0.09	1.01 ± 0.09	0.921
Total body BMC, g	2937 ± 404 (66)	2990 ± 346	0.426	1910 ± 292	1894 ± 286	0.709