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. 2014 Apr 3;9(4):e93574. doi: 10.1371/journal.pone.0093574

Table 1. Comparison of characteristics of patients who defaulted from TB treatment (cases) versus patients who completed TB treatment (controls): results of univariate analyses.

Characteristic Cases Controls p-value
(N = 91) (N = 186)
Sociodemographic characteristics
Age ≥50 years 6 (7) 36 (19) <0.01
Male gender (n, %) 80 (88) 111 (60) <0.001
Employment (n, %) <0.01
Unemployed 29 (32) 77 (42)
Student 0 11 (6)
Housewife 0 6 (3)
Part-time worker 18 (20) 22 (12)
Full-time worker 42 (46) 64 (35)
Salaried employee 2 (2) 5 (3)
Income** 0.04
<1800 dirhams/month 70 (80) 122 (68)
≥1800 dirhams/month 18 (20) 58 (32)
Educational level 0.027
Unable to read 28 (31) 56 (30)
Primary school 39 (43) 51 (28)
Secondary school 21 (23) 61 (33)
Attended university 3 (3) 17 (9)
Number of people living with patient (mean, sd) 3.91 (3) 4.90 (3) 0.0044
Years at current address 0.61
<1 6 (7) 8 (4)
1–3 9 (10) 15 (8)
>3 76 (84) 163 (88)
Disease and treatment factors
Pulmonary TB 88 (97) 109 (59) <0.001
Treatment type <0.001
First treatment 53 (58) 172 (92)
Retreatment 38 (42) 14 (8)
Treatment initiation to symptom resolution: 0.001
<2 months 77 (85) 121 (65)
≥2 months 14 (15) 65 (35)
Treatment side effects <0.01
None 65 (71) 113 (61)
Mild 15 (17) 62 (33)
Moderate 10 (11) 10 (5)
Severe 1 (1) 1 (1)
Treatment delivery <0.001
Daily DOT 30 (33) 15 (8)
No daily DOT 61 (67) 170 (92)
HIV seronegative 91 (100) 184(100) N/A
Diabetes mellitus 3 (3) 10 (5) 0.55
Mental illness 3 (3) 3 (2) 0.40
Current smoker 50 (55) 29 (16) <0.001
Current alcohol use 21 (23) 13 (7) <0.001
Current cannabis use 19 (21) 6 (3) <0.001
Access to care or social support
Can be reached by phone 46 (51) 96 (64) 0.046
Lives >5 km from clinic 14 (15) 20 (11) 0.27
Lives in rural area 13 (14) 28 (15) 0.84
Told about TB diagnosis
Family 84 (92) 180 (97) 0.10
Friends 45 (50) 113 (61) 0.07
Colleagues 12 (13) 24 (13) 0.95
Work interference with treatment <0.001
Work does not affect treatment 63(71) 179 (96)
Work interferes with treatment due to:
Long distance to clinic 4 (5) 1 (0.5)
Long work hours 7 (8) 3 (2)
Seasonal work 5 (6) 2 (1)
Another reason 10 (11) 0

**n = 268, 6 controls and 3 cases declined to respond to this question; median urban income in Morocco was 6,100 dirhams/month in 2009.