Table 3. Hazard ratios (HRs) and 95% confidence intervals (CIs) of herpes zoster among liver cirrhosis patients during the 1-, 3-, and 5-year follow-up periods from the index ambulatory visit or inpatient care in 1998–2005.

	1-year follow-up period		3-year follow-up period		5-year follow-up period
Development of herpes zoster	Patients with liver cirrhosis	Comparison cohort	Patients with liver cirrhosis	Comparison cohort	Patients with liver cirrhosis	Comparison cohort
Yes (%)	21 (0.4)	83 (0.4)	53 (1.1)	252 (1.1)	82 (1.8)	441 (1.9)
No (%)	4646 (99.6)	23252 (99.6)	4614 (98.9)	23,083 (98.9)	4585 (98.2)	22,894 (98.1)
Crude HR (95% CI)	1.27 (0.79–2.05)	1	1.05 (0.78–1.42)	1	0.93 (0.74–1.18)	1
Adjusted HR (95% CI)	1.16 (0.67–2.00)	1	0.83 (0.59–1.17)	1	0.77 (0.59–1.01)	1

Adjustments were made for patients’ gender, age, urbanization level, geographic region, monthly income, hypertension, diabetes, human immunodeficiency virus, organ transplantation, hepatitis B, hepatitis C, chronic renal failure, systemic lupus erythematous, rheumatoid arthritis, chronic obstructive pulmonary disease, cancer, and alcoholism.