Table 4. Gene-gene interaction of RNASEL and MIR146A in relation to non-melanoma skin cancer risk.

Genotypes		Controls	BCC		SCC
MIR146A	RNASEL	N	N	OR (95% CI)*	N	OR (95% CI)*
G/G	G/G	177	218	reference	137	reference
	G/A or A/A	259	310	1.07 (0.82–1.41)	204	1.02 (0.75–1.39)
G/C or C/C	G/G	96	140	reference	114	reference
	G/A or A/A	195	162	0.57 (0.40–0.80)	129	0.56 (0.38–0.81)
				P-interaction = 0.005		P-interaction = 0.012

*Adjusted for age, sex, level of education, cigarette smoking status 1 year before the reference date (for SCC only), skin sensitivity (measured by skin reaction after 1 hour of sun exposure the first time in the summer), and the number of lifetime painful sunburns.