Table 2. Characteristics of the fetuses, assigned to four subgroups according to the category of CHD.
| Right outflow obstruction(n = 42) | Left outflow obstruction(n = 46) | TGA (n = 9) | Other CHDs (n = 22) | |
| Male/Female | 25/17 | 26/20 | 7/2 | 12/10 |
| Gestational age (wks) | 28.0 (24.0–31.0) | 26.5 (23.0–32.0) | 27.0 (24.0–33.0) | 26.0 (23.3–31.8) |
| BW (g) | 1050 (393–1710) | 950 (473–1623) | 900 (720–1850) | 895 (407–1825) |
| LW (g) | 23.3 (6.6–30.3) | 21.8(13.3–29.6) | 25.0 (18.0–45.0) | 17.9 (9.7–31.5) |
| LW (% of sample mean)§ * | 90.8 (59.1–113.0) | 112.0 (84.5–124.1)# | 124.5 (105.6–129.8)# | 97.0 (71.8–102.4) |
| Residual (g)§ * | −1.4 (−5.4–3.1) | 1.5 (−2.4–4.3)# | 4.9 (0.9–9.4)# | −1.1 (−3.7–0.5) |
| LW/BW * | 0.021 (0.014–0.026) | 0.024 (0.018–0.029)# | 0.025 (0.024–0.025) | 0.019 (0.015–0.023) |
| LW/BW (% of expected) ¶ * | 80.6 (56.7–101.7) | 97.1 (76.9–109–0)# | 105.3 (91.7–114.8)# | 84.2 (66.0–93.3) |
| Chromosomal abnormality (%) | 16.2 | 11.6 | 0 | 33.3 |
| Any associated extracardiac abnormality | 16.7 | 19.6 | 0 | 31.8 |
Values are medians (IQR) or n (% of each subgroup). BW: body weight; LW: lung weight. § The mean values for the population and the residuals are derived from the regression model relating LW and BW (see text and Figure S1);
¶
expected values derived from [18];
*p value<0.05 in multiple group analysis;
#p value <0.05 when comparing each subgroup with the one with right outflow obstruction.