Table 4. Characteristics of the fetuses, assigned to two subgroups according to the association of PH with CHD.
CHD and no PH (n = 104) | CHD and PH (n = 15) | |
Male | 60 (58) | 10 (67) |
Gestational age (wks) | 27.0 (24.0–32.0) | 25.0 (22.0–29.5) |
BW (g) | 965 (557–1715) | 580 (225–1905) |
LW (g) | 23.55 (13.35–32.90) | 2.50 (1.65–13.64)** |
LW/BW | 0.023 (0.019–0.028) | 0.007 (0.005–0.010)** |
LW/BW (% of expected) | 93.1 (77.3–107.8) | 30.7 (20.1–38.1)** |
Chromosomal abnormality | 12/93 (13) | 5/13 (38)* |
Any associated extracardiac abnormality | 68 (65) | 12 (80) |
IUGR | 11 (11) | 2 (13) |
Renal hypoplasia | 7 (7) | 2 (13) |
Omphalocele | 3 (3) | 1 (7) |
Thoracic dystrophy | 1 (1) | 0 (0) |
Hydrothorax | 0 (0) | 1 (7) |
Right outflow obstruction | 33 (32) | 9 (60)* |
Left outflow obstruction | 42 (40) | 4 (27) |
TGA | 9 (9) | 0 (0) |
Other CHDs | 20 (19) | 2 (13) |
Values are medians (IQR) or n (% of each subgroup). BW: body weight; LW: lung weight.
*P value<0.05;
**P value<0.0001.