Table 5. Univariate and multivariate analyses assessing the risk of PH as a function of CHD category, presence of an abnormal karyotype and the presence of a malformation likely to interfere with lung growth (IUGR, renal hypoplasia, omphalocele, thoracic dystrophy, or hydrothorax).
Variable | OR | 95% CI | p value |
Univariate analysis | |||
CHD with right outflow obstruction | 3.227 | 1.061–9.817 | 0.039 |
Abnormal karyotype | 4.219 | 1.183–15.041 | 0.026 |
Associated extracardiac abnormality | 2.389 | 0.728–7.834 | 0.151 |
Multivariate analysis | |||
CHD with right outflow obstruction | 3.812 | 1.094–13.281 | 0.036 |
+ Abnormal karyotype | 4.619 | 1.218–17.507 | 0.024 |
CHD with right outflow obstruction | 4.353 | 1.193–15.875 | 0.026 |
+ Abnormal karyotype | 3.737 | 0.941–14.848 | 0.061 |
+ Associated extracardiac abnormality | 2.716 | 0.684–10.787 | 0.156 |