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. 2014 Apr 3;9(4):e93557. doi: 10.1371/journal.pone.0093557

Table 5. Univariate and multivariate analyses assessing the risk of PH as a function of CHD category, presence of an abnormal karyotype and the presence of a malformation likely to interfere with lung growth (IUGR, renal hypoplasia, omphalocele, thoracic dystrophy, or hydrothorax).

Variable OR 95% CI p value
Univariate analysis
CHD with right outflow obstruction 3.227 1.061–9.817 0.039
Abnormal karyotype 4.219 1.183–15.041 0.026
Associated extracardiac abnormality 2.389 0.728–7.834 0.151
Multivariate analysis
CHD with right outflow obstruction 3.812 1.094–13.281 0.036
+ Abnormal karyotype 4.619 1.218–17.507 0.024
CHD with right outflow obstruction 4.353 1.193–15.875 0.026
+ Abnormal karyotype 3.737 0.941–14.848 0.061
+ Associated extracardiac abnormality 2.716 0.684–10.787 0.156