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. 2014 Apr 3;9(4):e93756. doi: 10.1371/journal.pone.0093756

Table 2. Univariate survival analyses of CRC patients according to various clinicopathological variables.

Variable n 5-year CCSS (%) Log rank χ2 test P
Years of diagnosis 333.65 P<0.001
1988–1993 16017 70.9%
1994–1999 21295 74.6%
2000–2003 32523 78.3%
Sex 105.86 P<0.001
male 37130 74.4%
female 32705 76.7%
Age 35.84 P<0.001
≤40 3014 78.6%
41–74 66821 75.3%
Race 195.16 P<0.001
Caucasian 55824 76.0%
African American 7390 69.3%
Others* 6621 78.1%
Primary site 144.24 P<0.001
Colon cancer 51372 76.1%
Rectal cancer 18463 73.6%
Pathological grading 1128.17 P<0.001
High/Moderate 54812 78.3%
Poor/undifferentiation 12644 63.5%
Histological Type 584.49 P<0.001
Adenocarcinoma 61384 76.3%
Mucinous cancer 7804 71.7%
Signet-ring cancer 647 42.6%
AJCC stage 7353.52 P<0.001
I 4563 96.2%
II 35867 85.4%
III 29405 60.1%
No. of LNs dissected 36.93 P<0.001
<12 37653 74.7%
≥12 32182 76.3%
Metastasis LNR 11590.57 P<0.001
rN0(0) 40546 86.6%
rN1(0.01–0.20) 12814 72.3%
rN2(0.21–0.60) 11482 56.3%
rN3(>0.60) 4993 36.8%

*including other (American Indian/AK Native, Asian/Pacific Islander) and unknowns.