Table 5. Distribution frequency of clinical status and CD44 rs187115 genotype frequencies in 599 patients with oral cancers.

	genotypic frequencies
Variable	AA(N = 336) n (%)	AG+ GG(N = 263) n (%)	OR (95% CI)	AOR (95% CI)
Clinical Stage
Stage I/II	163 (48.5%)	101 (38.4%)	1.00	1.00
Stage III/IV	173 (51.5%)	162 (61.6%)	1.511 (1.089–2.098) p  = 0.013 *	1.619 (1.124–2.333) p  = 0.010 *
Tumor size
≦ T2	212 (63.1%)	151 (57.4%)	1.00	1.00
> T2	124 (36.9%)	112 (42.6%)	1.268 (0.912–1.764) p = 0.158	1.314 (0.910–1.899) p = 0.145
Lymph node metastasis
No	217 (64.6%)	165 (62.7%)	1.00	1.00
Yes	119 (35.4%)	98 (37.3%)	1.083 (0.774–1.515) p = 0.641	1.075 (0.742–1.557) p = 0.702
Distant metastasis
No	334 (99.4%)	257 (97.7%)	1.00	1.00
Yes	2 (0.6%)	6 (2.3%)	3.899 (0.780–19.477) p = 0.074	9.427 (0.892–99.624) p = 0.062
Cell differentiation
Well	42 (12.5%)	101 (14.4%)	1.00	1.00
Moderately or poorly	294 (87.5%)	162 (85.6%)	0.846 (0.528–1.356) p = 0.487	0.905 (0.543–1.506) p = 0.700

The ORs with 95% CIs were estimated by logistic regression models.

The AORs with 95% CIs were estimated by multiple logistic regression models after controlling for age, gender, alcohol consumption, and tobacco use.

> T2: tumor size >2 cm in the greatest dimension.

*p value <0.05 as statistically significant.