Figure 4. Pseudogene transcription increases the mean and variance of parental gene expression.

A) A cartoon illustrating the computational procedure. For each pseudogene, we computed the means (μ_h and μ_l) and variances (S_h and S_l) of its parental gene expression values in the 8 tissue samples with more pseudogene transcripts and the 8 with fewer pseudogene transcripts. Distribution of mean (B) and variance (C) differences for all transcribed pseudogenes, pseudogenes with positive (ρ_pg:g>0.2) and negative (ρ_pg:g<−0.2) transcriptional correlation with their parents.