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. 2014 Apr 3;9(4):e93972. doi: 10.1371/journal.pone.0093972

Table 1. Top pseudogene candidates of three different types of predicted functional potentials (ND, not determined). The full lists can be found in Table S1.

Pseudogene Genomic Location Parental gene Transcribed strand ρpg:g Note
A. miRNA decoy
PTENP1 chr9:33673502-33677497 (−) PTEN sense 0.87 Compete with PTEN for miRNA binding [28].
FAM92A1P1 chr15:41455322-41456695 (+) FAM92A1 sense 0.80
MYLKP1 chr3:75377700-75388222 (−) MYLK sense 0.94 Promote cell proliferation [100], but miRNA involvement unknown.
CROCCP3 chr1:16802411-16817802 (−) CROCC sense 0.70
ABCC6P2 chr16:14914649-14918526 (−) ABCC6 NA 0.50
RP11-321E8 chr7:63929563-63931031 (+) ZNF680 sense 0.39
B. siRNA repressing coding gene
ψPPM1K chr4:89179936-89180414 (−) PPM1K antisense ND Target both NEK8 and PPM1K gene and suppress cell growth [30]. Not annotated by GENCODE.
ATP8A2P1 chr10:37537046-37604729 (+) ATP8A2 antisense −0.22 KD inhibited cell proliferation [12]
HMGA1P7 chr6:134435733-134436628 (−) HMGA1 antisense −0.25
CNN2P1 chr22:30442265-30443182 (−) CNN2 antisense −0.32
RP11-553K8.3 chr1:198648263-198649162 (−) PEBP1 NA −0.56
MSNP1 chr5:25909612-25911343 (+) MSN sense −0.5 Antisense ncRNA was reported [19]
RP11-159C21.4 chr1:53237865 -53238320(−) RPS13 sense 0.52
C. siRNA mediating H3K9me3 enrichment
MTND4P12 chr5:134262350-134263726(−) MTND4 both ND
RP5-857K21.6 chr1:566454-567996(+) MT-CO1 sense ND
SDHAP2 chr3:195384967-195412775(+) SDHA ND 0.54
FTLP3 chr20:4004564-4005091(+) FTL sense ND
RP11-7G23.4 chr9:45729709-45730417(+) FAM27A ND ND