Figure 4. Expression of Ci155 leads to a downregulation of Su(fu) in the developing eye and wing. (A and F) Wild type expression patterns of Su(fu) in third instar eye and wing discs. (B–E) Overexpression of full-length Ci in flp-out clones (hsFLP; Act > y+ > GAL4, UAS-RFP/UAS-Ci: RFP positive cells in D and E) leads to the downregulation of Su(fu) in the developing eye. (G–J) Flp-out clones overexpressing Ci in the wing (same genotypes as in B-E: RFP positive cells in I and J) also show a reduction in Su(fu) expression.