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. Author manuscript; available in PMC: 2015 Mar 4.
Published in final edited form as: Structure. 2014 Feb 13;22(3):397–408. doi: 10.1016/j.str.2013.12.018

Figure 3. Structural Basis for PI(4)P Recognition and High-Affinity Binding.

Figure 3

(A) Dibutyl PI(4)P and waters from the final refined model overlaid with electron density from the σA-weighted 2|Fo| - |Fc| map calculated before addition of the ligand/solvent and contoured at 1.0 σ.

(B) Polar contacts between DrrA and the lower (left) and upper (right) regions of dibutyl PI(4)P.

(C) View of the P4M domain and dibutyl PI(4)P colored according to buried surface area upon complex formation.