TABLE 3.
Summary of the β1-subunit effect on the different properties of BKCa channel α-subunit N-terminal isoforms
Isoform | Voltage dependence | Conductance | Open dwell time constants | Close dwell time constants | Burst duration | Interburst interval |
---|---|---|---|---|---|---|
MANG | Leftward shift | No change | Both increased | Decreased | No change | Increased |
MSSN | No shift | No change | Only τ2 increased | Increased | Increased | Increased |
MDAL | Larger leftward shift | Decreased | Both increased | Decreased | Increased | No change |