Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr;24(4):592–603. doi: 10.1101/gr.166751.113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Spieler et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

PMC Copyright notice

Figure 6. — Motor restlessness/hyperactivity in adult heterozygous Meis1^tm1Mtor mice. Heterozygous Meis1^tm1Mtor (het) traveled a higher total distance (P = 0.003, two-tailed t-tests, n = 29) (A) and moved with a higher speed on average (P = 0.004, two-tailed t-tests, n = 30) (B) in a 20-min open field test for spontaneous locomotor activity in a novel environment. (C) Oxygen consumption (mL/h) plotted versus body mass (g). Scatterplot with regression lines split by sex and genotype to adjust for body mass variation. The shift in regression lines indicates higher energy turnover in heterozygous Meis1^tm1Mtor mice (linear regression model, P = 0.0005). (D) Mean distance traveled (cm/20 min) monitored by infrared light beams during the indirect calorimetry trial. Heterozygous Meis1^tm1Mtor mice tended to show increased locomotor activity under home cage conditions (two-way ANOVA, P = 0.06).