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. 2014 Mar 28;8:88. doi: 10.3389/fncel.2014.00088

FIGURE 9.

FIGURE 9

Effects of maternal D-CSA administration on the distribution of radially migrating neurons in the fetal neocortex. (A,B) Fluorescent micrographs showing the distribution of RFP-labeled radially migrating cells in cortical sections from GAD67GFP/GFP fetuses at E17.5. Saline (Control) (A) or D-CSA (B) was administered to the mothers every 12 h for 3 days (E14–17). (C) The averaged proportions of radially migrating cells in the CP, SP, IZ, and SVZ/VZ regions of cortical slices obtained from GAD67+/+ (leftmost), GAD67+/GFP (middle), and GAD67GFP/GFP (rightmost) fetuses at E17.5 with (yellow bars) and without (blue bars) maternal D-CSA administration. (D) The averaged proportions of radially migrating cells in cortical slices obtained from GAD67GFP/GFP fetuses at E16.5 (left) and E18.5 (right) either with (yellow bars) or without (blue bars) maternal D-CSA administration. The numbers in parentheses indicate the number of fetuses examined. $P < 0.05 by χ2-test. *P < 0.05 by MWU-test. Error bar: mean ± SEM. Scale bar: 200 μm.