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. Author manuscript; available in PMC: 2015 Mar 14.

Published in final edited form as: Vaccine. 2014 Jan 30;32(13):1466–1472. doi: 10.1016/j.vaccine.2014.01.033

Table 2.

Association between HIV infection and protective levels of pneumococcal capsular IgG antibodies (≥ 0.35 μg/mL) by serotype.

Serotype	Maternal Samples		Cord Samples
	OR (95%CI)	aOR (95% CI)^a	OR (95%CI)	aOR (95% CI)^b
1	0.98 (0.52–1.86)	0.84 (0.40–1.74)	0.34 (0.16–0.76)^*	0.20 (0.07–0.56)^*
4	0.30 (0.15–0.60)^*	0.28 (0.12–0.63)^*	0.18 (0.07–0.43)^*	0.10 (0.03–0.33)^*
5	0.40 (0.22–0.75)^*	0.44 (0.22–0.90)^*	0.14 (0.07–0.29)^*	0.13 (0.05–0.34)^*
6B	0.68 (0.37–1.25)	0.81 (0.41–1.63)	0.51 (0.27–0.95)^*	0.61 (0.26–1.40)
9V	0.46 (0.25–0.85)^*	0.53 (0.26–1.05)	0.31 (0.16–0.59)^*	0.38 (0.16–0.87)^*
14	0.37 (0.13–1.06)	0.33 (0.11–1.02)	0.38 (0.15–0.96)^*	0.26 (0.07–0.93)^*
18C	0.49 (0.26–0.93)^*	0.59 (0.28–1.22)	0.25 (0.13–0.48)^*	0.28 (0.12–0.64)^*
19F	0.43 (0.20–0.90)^*	0.45 (0.19–1.02)	0.20 (0.10–0.38)^*	0.12 (0.05–0.32)^*
23F	0.28 (0.15–0.53)^*	0.27 (0.13–0.57)^*	0.19 (0.09–0.36)^*	0.15 (0.06–0.39)^*

OR: odds ratio; CI: confidence interval; aOR: adjusted odds ratio

^a

adjusted for maternal age and maternal education (> primary education)

^b

adjusted for maternal age, maternal gravidity, normal Apgar score at 1 minute postpartum (≥ 7) and infant birth weight (Kg)

^*

indicates significantly reduced odds of having protective pneumococcal capsular IgG antibody level ≥ 0.35 μg/ml