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. 2014 Mar 6;15(3):4060–4076. doi: 10.3390/ijms15034060

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© 2014 by the authors; licensee MDPI, Basel, Switzerland

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Figure 2. — Bioinformatics analysis of HOTAIR loss in Bel-7402 HCC cell line. (A) Gene ontology analysis of HOTAIR knockdown microarray data using the DAVID program. Red bars represent the top hits for upregulated genes. Blue bars represent the top hits for downregulated genes. DAVID enrichment scores are represented with Benjamini-Hochberg-adjusted p values. All error bars in this figure are mean ± S.E.M.; (B) KEGG pathway analysis of HOTAIR knockdown microarray data. Green bars represent the percentage of transcriptional domain coverage; and (C) mRNA-signaling pathway integrated network based on the predicted interactions (partial).

Figure 2. — Bioinformatics analysis of HOTAIR loss in Bel-7402 HCC cell line. (A) Gene ontology analysis of HOTAIR knockdown microarray data using the DAVID program. Red bars represent the top hits for upregulated genes. Blue bars represent the top hits for downregulated genes. DAVID enrichment scores are represented with Benjamini-Hochberg-adjusted p values. All error bars in this figure are mean ± S.E.M.; (B) KEGG pathway analysis of HOTAIR knockdown microarray data. Green bars represent the percentage of transcriptional domain coverage; and (C) mRNA-signaling pathway integrated network based on the predicted interactions (partial).