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. 2014 Mar 6;15(3):4060–4076. doi: 10.3390/ijms15034060

Table 1.

Relationship between RBM38 expression and clinicopathological features of 53 hepatocellular carcinoma (HCC) patients.

Variables N = 53 RBM38 expression χ2 p value

high low
Age (years)

≤50 21 6 (11.3%) 15 (28.3%) 0.083 0.773
>50 32 8 (15.1%) 24 (45.3%)

Gender

Male 44 13 (24.5%) 31 (58.5%) 1.306 0.253
Female 9 1 (1.9%) 8 (15.1%)

Size of tumor (cm)

≤5 32 7 (13.2%) 25 (47.2%) 0.856 0.355
>5 21 7 (13.2%) 14 (26.4%)

Number of tumor

Single 29 8 (15.1%) 21 (39.6%) 0.045 0.832
Multiple 24 6 (11.3%) 18 (33.9%)

Vascular invasion

Negative 41 11 (20.8%) 30 (56.6%) 0.016 0.899
Positive 12 3 (5.7%) 9 (17.0%)

Pathological Grading

Well/Moderately 25 5 (9.4%) 20 (37.7%) 1.002 0.317
Poorly 28 9 (17.0%) 19 (35.8%)

AFP (ng/mL)

≤400 20 9 (17.0%) 11 (20.8%) 5.708 0.017
>400 33 5 (9.4%) 28 (52.8%)

TBIL (μmol/L)

≤20 33 10 (18.9%) 23 (43.4%) 0.680 0.410
>20 20 4 (7.5%) 16 (30.2%)

AFP, alpha-fetoprotein; TBIL, total bilirubin; Statistical analyses were performed with Pearson’s chi-square test.