Mean lesion area and the changes in gastric blood flow (GBF) after application of a small “protective” dose of capsaicin (CAP, 0.25 mg/kg i.g.), l-arginine (l-Arg, 200 mg/kg i.g.) or CGRP (10 μg/kg s.c.). Each was applied alone and in combination with ADMA (20 mg/kg i.g.), followed by exposure to ischemia/reperfusion. Results are mean ± S.E.M of 6–8 rats per group. Significant change (p < 0.05) as compared with the respective values in the vehicle-control group, is indicated by an asterisk. A cross indicates a significant change (p < 0.05) compared to the values obtained in the vehicle-control group. An asterisk and a cross indicate a significant change (p < 0.05) as compared to the values obtained in rats treated with vehicle, capsaicin, l-arg, or CGRP without ADMA.