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. 2014 Mar 21;15(3):5115–5127. doi: 10.3390/ijms15035115

Figure 1.

Figure 1.

The structural parameters do not indicate a tautomeric equilibrium but a single amino/amido form. The main differences between the two crystalline forms lie in the intramolecular hydrogen of NH2 bonding and its relative orientation to oxygen of amide [28]. Attractive intramolecular interactions occur and are responsible for the closure of pharmacophore site (C=Oδ−–NH2 δ+).