Fig. 6.

Effect of apigenin on fluoride-induced increases in phospho-MYPT1 levels. Phospho-MYPT1 protein levels were significantly decreased in quick frozen apigenin-treated rat aorta in the absence of endothelium compared to vehicle-treated rat aorta precontracted with fluoride. The upper panel shows a typical blot and the lower panel shows average densitometry results for relative levels of phospho-MYPT1. Data are expressed as the means of 3–5 experiments with vertical lines representing SEMs. ^*p<0.05, ^##p<0.01, versus control or normal group respectively. Apigenin: 0.1 mM apigenin; Fluoride: 6 mM sodium fluoride.