Table 3.
Results of drug susceptibility testing of 19 Malassezia sp. isolates, as determined by Neo-Sensitabs assay
| Malassezia sp. (no.) |
Antifungal drug
a
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
CPO |
FLZ |
KTZ |
ITZ |
ECZ |
MNZ |
|||||||
| Zone [mm] b | Cat. (no.) c | Zone [mm] | Cat.(no.) | Zone [mm] | Cat. (no.) | Zone [mm] | Cat. (no.) | Zone [mm] | Cat. (no.) | Zone [mm] | Cat. (no.) | |
|
M. sympodialis (13) |
28 |
S (13) |
43 |
S (13) |
33.9 |
S (13) |
36.5 |
S (13) |
24.5 |
S (12) |
26.5 |
S (13) |
| 17 |
I (1) |
|||||||||||
|
M. furfur (2) |
23 |
S (2) |
36 |
S (2) |
30 |
S (1) |
29 |
S (2) |
15.5 |
I (2) |
20 |
S (1) |
| 25 |
I (1) |
|||||||||||
| 17 |
I (1) |
|||||||||||
|
M. furfur + M. sympodialis (2) |
22.5 |
S (2) |
39 |
S (2) |
25.5 |
I (2) |
28.5 |
S (2) |
14.5 |
I (2) |
20 |
S (1) |
| 15 |
I (1) |
|||||||||||
|
M. slooffiae (1) |
30 |
S (1) |
45 |
S (1) |
35 |
S (1) |
45 |
S (1) |
30 |
S (1) |
20 |
S (1) |
| M. slooffiae + M. sympodialis (1) | 30 | S (1) | 40 | S (1) | 40 | S (1) | 40 | S (1) | 30 | S (1) | 16.5 | I (1) |
a CPO, ciclopirox; FLZ, fluconazole; KTZ, ketoconazole; ITZ, itraconazole; ECZ, econazole; MNZ, miconazole; number of isolates are given in brackets.
b Inhibition zone diameter mean value [mm] (each isolated was tested twice).
c Susceptibility categorization (S, susceptible; I, intermediate; R, resistant) based on the following criteria: CPO, ECZ, MNZ: S, ≥ 20; I, 12–19; R, ≤ 11; FLZ: S, ≥ 22; I, 15–21; R, ≤ 14; ITZ: S, ≥ 16; I, 10–15; R, < 10; KTZ: S, ≥ 30; I, 23–29; R, ≤ 22.