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. Author manuscript; available in PMC: 2014 Apr 4.
Published in final edited form as: Mol Cancer Res. 2013 Jul 15;11(10):1223–1234. doi: 10.1158/1541-7786.MCR-13-0252-T

Fig. 2.

Fig. 2

53BP1 deficiency aggravates the NHEJ defect in primary Atm−/− cells. A, cells were irradiated and the number of γ-H2AX foci per nucleus quantified by indirect immunofluorescence. N=100 cells per histogram. B, representative examples of cells in A. C, mice were irradiated, allowed to repair in vivo and euthanized at the indicated timepoints. The number of γ-H2AX foci per nucleus was quantified in thymus cryosections by indirect immunofluorescence. N=150 cells per histogram.