Table 5.
Comparison of clinical features between giant cell interstitial pneumonia (GIP) group and fibrosis group
| GIP group (n=14) |
Fibrosis group (n=5) |
p Value | |
|---|---|---|---|
| Age (years) | 43.1±10.8 | 58.6±5.41 | 0.007 |
| Gender (M/F) | 7/7 | 5/0 | 0.106 |
| Exposure duration (months) | 73.0±48.8 | 285.6±140.3 | 0.007 |
| Pneumothorax (+/−) | 6/8 | 2/3 | 1.000 |
| KL-6 (U/mL) | 398.7±189.4 | 710.8±297.7 | 0.023 |
| SP-D (ng/mL) | 260.3±257.5 | 161.0±54.75 | 0.903 |
| PaO2 (Torr) | 84.3±14.3 | 84.4±11.2 | 0.922 |
| PaCO2 (Torr) | 42.8±2.75 | 56.0±34.6 | 0.657 |
| VC, % predicted (%) | 64.4±27.1 | 65.5±24.1 | 0.734 |
| FEV1 (L) | 1.63±0.23 | 1.88±0.32 | 0.537 |
| FEV1/FVC (%) | 85.4±12.9 | 86.1±2.62 | 0.910 |
| DLco, % predicted (%) | 50.8±16.7 | 57.2±18.8 | 0.371 |
| Bronchoalveolar lavage | |||
| Total cell count (×105/mL) | 3.52±2.41 | 2.26±0.96 | 0.395 |
| Lymphocytes (%) | 31.5±23.0 | 8.40±9.08 | 0.015 |
| CD4/8 ratio | 0.76±0.51 | 3.22±4.85 | 0.298 |
DLco, carbon monoxide diffusing capacity; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; KL-6, Krebs von den Lungen 6; SP-D, surfactant protein D; VC, vital capacity.