Table 1.
Medication Adherence and Baseline Demographic and Clinical Features.
| Adherent Group** (N=191)# | Non-Adherent Group (N=9)# | Test Statistic (df) | P-value | |
|---|---|---|---|---|
| Age | ||||
| Mean±SD (N) | 39.9±12.0 (191) | 40.3±14.1 (9) | 0.01 (1) | 0.925 |
| Range (min,max) | (18.0,65.0) | (20.0,68.0) | ||
| Median | 40.0 | 37.0 | ||
| Gender | 2.57 (1) | 0.109 | ||
| Male | 39.8% (76/191) | 66.7% (6/9) | ||
| Female | 60.2% (115/191) | 33.3% (3/9) | ||
| Ethnicity | 0.24 (1) | 0.626 | ||
| Hispanic or Latino | 17.4% (33/190) | 11.1% (1/9) | ||
| Not Hispanic or Latino | 82.6% (157/190) | 88.9% (8/9) | ||
| Marital status | 5.13 (4) | 0.274 | ||
| Single | 31.9% (61/191) | 22.2% (2/9) | ||
| Divorced or separated | 23.6% (45/191) | 55.6% (5/9) | ||
| Married or living as married | 31.4% (60/191) | 11.1% (1/9) | ||
| Widowed | 2.1% (4/191) | 0.0% (0/9) | ||
| Never married | 11.0% (21/191) | 11.1% (1/9) | ||
| Diagnosis | 0.00 (1) | 0.955 | ||
| Bipolar I | 77.0% (147/191) | 77.8% (7/9) | ||
| Bipolar II | 23.0% (44/191) | 22.2% (2/9) | ||
| CGI-Severity | 0.29 (1) | 0.591 | ||
| Mean±SD (N) | 4.3±0.9 (191) | 4.1±0.6 (9) | ||
| Range (min,max) | (1.0,7.0) | (3.0,5.0) | ||
| Median | 4.0 | 4.0 | ||
| MADRS | 0.09 (1) | 0.764 | ||
| Mean±SD (N) | 22.2±10.3 (191) | 21.1±11.0 (9) | ||
| Range (min,max) | (2.0,49.0) | (5.0,36.0) | ||
| Median | 23.0 | 23.0 | ||
| YMRS | 0.10 (1) | 0.757 | ||
| Mean±SD (N) | 12.8±7.9 (191) | 13.7±8.5 (9) | ||
| Range (min,max) | (0.0,39.0) | (2.0,28.0) | ||
| Median | 12.0 | 15.0 | ||
| LIFE-RIFT | 0.11 (1) | 0.735 | ||
| Mean±SD (N) | 20.8±6.4 (191) | 20.1±4.5 (9) | ||
| Range (min,max) | (6.0,37.0) | (14.0,25.0) | ||
| Median | 20.0 | 22.0 | ||
| Suicide Attempts | 0.05 (1) | 0.825 | ||
| Yes | 40.7% (77/189) | 44.4% (4/9) | ||
| No | 59.3% (112/189) | 55.6% (5/9) | ||
| Any Anxiety Disorder | 1.31 (1) | 0.252 | ||
| No | 36.6% (70/191) | 55.6% (5/9) | ||
| Yes | 63.4% (121/191) | 44.4% (4/9) | ||
| Any Substance Disorder | 1.46 (1) | 0.226 | ||
| No | 46.1% (88/191) | 66.7% (6/9) | ||
| Yes | 53.9% (103/191) | 33.3% (3/9) | ||
Note.
**
Adherence is defined as missing less than 30% of their daily medication doses.
#
sample was reduced from 283 to 200 due to missing TRQ data at baseline.