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Schematic representation of RNA-tethering system used to probe the contribution of specific RNAs in the formation of nuclear bodies. The hypothetical transcript is tagged with one bacteriophage MS2 stem loop in the 3′ UTR. The monomeric LacI-NLS-GFP-MS2 coat protein selectively binds the MS2 loop and targets the MS2-tagged transcripts to the LacO array where they accumulate
