Table 1.

The total number of PSD-95-positive puncta in the dorsal raphe of Ovx monkeys treated with placebo, E, P or E+P (n = 3/group).

Set	Ovx	E	P	E+P	F-values
1	13294133	18746336	18559261	19817792
2	13621572	17031957	17718689	20687377
3	6590748	8127561	9514303	7161746
	11168818 ± 2290986	14635285 ± 3291283*	15264084 ± 2885113*	15888972 ± 4370827*	F(3,11) = 5.08, P < 0.05

The number of puncta for PSD-95 was totaled for 4 anatomical levels, generating one overall total per monkey. Tissue for PSD-95 was processed in 3 different sets containing 1 animal of each treatment group. Sets 1 and 2 were conducted simultaneously, whereas Set 3 was conducted a year later when additional monkeys were obtained. Data values in bold are mean±SEM. There was a significant difference between groups in the total number of puncta (ANOVA for matched samples P = 0.0438).

^*E, P and E+P greater than Ovx with Newman–Keul’s, P<0.05 all.