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. 2014 Feb 28;15:35. doi: 10.1186/1471-2202-15-35

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Copyright © 2014 Le Coz et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Time course of serum corticosterone levels in response to CCI of the right sciatic nerve. Basal corticosterone levels (day 0) were highest in FIS and lowest in LEW rats, however without reaching significance levels due to a high variance in the FIS strain. Induction of neuropathy led to an increase of the corticosterone concentration in all three strains in the first days. The levels subsequently decreased and ended up below baseline values in FIS rats or above in LEW. Data are shown as mean ± s.e.m.