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. 2014 Feb 18;21(1):15. doi: 10.1186/1423-0127-21-15

Table 1.

The PAMPA-BBB permeation of BBD

Compound Pe (10 -6 cm/s) Known Pe (10 -6 cm/s) Classification
Theophylline
0.08 ± 0.01
0.12 ~ 0.18
BBB-
Verapamil
23.82 ± 1.82
16 ~ 23
BBB+
Testosterone
34.08 ± 4.78
17
BBB+
BBD
20.87 ± 3.05
-
BBB+
Sesamin 0.00 ± 0.01 - BBB-