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. Author manuscript; available in PMC: 2014 Apr 4.
Published in final edited form as: J Gastrointest Surg. 2008 Aug 21;12(10):1745–1753. doi: 10.1007/s11605-008-0633-5

Figure 1.

Figure 1

Overview of the genes involved in the WNT signaling pathway. When the pathway is turned on by binding of WNT, a cascade of events leads to translocation of β-catenin to the nucleus, which in turn upregulates the expression of many cancer-related genes.