Table 4.
Polymorphisms at known drug resistance positions of HIV-1 subtype B among chronically infected patients from Northwest Ethiopia (N = 160)
| Drug class | Polymorphisms | Number of cases | Frequency (%) |
|---|---|---|---|
|
NRTI
|
|
16 |
10.0 |
| |
M41R/N |
2/1 |
1.9 |
| |
D67E/G/K |
1/1/1 |
1.9 |
| |
Q151P/Q/R |
1/1 |
1.3 |
| |
M184L/M |
4 |
2.5 |
| |
T215A/P/T |
3/1 |
2.5 |
|
NNRTI
|
|
52 |
33.5 |
| |
A98S/Q |
38/1 |
24.4 |
| |
L100V |
1 |
0.6 |
| |
K101R/X |
3/1 |
2.5 |
| |
K103E/R |
2 |
1.3 |
| |
V108T |
1 |
0.6 |
| |
E138Y/D |
1/1 |
1.3 |
| |
G190 D/R |
1/1 |
1.3 |
|
PR
|
|
11 |
6.9 |
| |
V32A/V |
1 |
0.6 |
| |
L10I |
3 |
1.9 |
| |
L10V |
2 |
1.3 |
| |
L10L/R |
1 |
0.6 |
| |
V11I/V |
1 |
0.6 |
| |
V11F/V |
1 |
0.6 |
| |
V11G/V |
1 |
0.6 |
| F53L | 1 | 0.6 |
Keys: Numbers correspond to amino acid positions. The first letter corresponds to the wild-type amino acid; the substituted amino acid is coded by the last letter.