Table 1.

The Tc values of clots tested were measured with a conventional CCD recorder

Clot type	Tc value ± SD (sec)
Clot/PBS	210.80±2.56*
Clot/NP	131.00±2.80*
Clot/ANP	93.67±2.19*
Clot/FNP	128.00±6.08*

Notes: The Tc values of clots with various CS NPs were significantly lower than that of clot/PBS, while that of clot/ANP was the lowest. The CCD recorder and QCM showed similar trends in Tc values. (*P<0.05 or better) (n=4).

Abbreviations: ANP, adenosine diphosphate–decorated chitosan nanoparticle; CCD, charge-coupled device; CS NP, chitosan nanoparticle; Clot/ANP, clot induced in ANP solution; Clot/FNP, clot induced in FNP solution; Clot/NP, clot induced in CS NP solution; Clot/PBS, clot induced in phosphate-buffered solution; CS NP, chitosan nanoparticle; FNP, fibrinogen-decorated chitosan nanoparticle; PBS, phosphate-buffered solution; QCM, quartz crystal microbalance; SD, standard deviation; Tc, clotting time.