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. Author manuscript; available in PMC: 2014 Apr 4.
Published in final edited form as: J Urol. 2012 Aug 15;188(4):1131–1136. doi: 10.1016/j.juro.2012.06.009

Table 1. Baseline characteristics of the study population.

Variable Overall (n=167) No biopsy reclassification (n=104) Biopsy reclassification (n=63) p-value

Age (yr)
 Mean ± SD 65.7 ± 4.8 65.6 ± 4.5 65.8 ± 5.2 0.7164
 Median (Range) 65.8 (50.6-76.1) 65.8 (55.0-74.9) 66.3 (50.6-76.1)

tPSA (ng/ml)
 Mean ± SD 4.9 ± 3.1 4.5 ± 3.4 5.6 ± 2.3 0.0004
 Median (Range) 4.6 (0.40-18.6) 3.86 (0.4-18.6) 5.31 (1.47-13.1)

Prostate volume
 Mean ± SD 50.88±22.38 51.95 ± 25.31 49.07 ± 16.34 0.7663
 Median (Range) 48.0 (10-145.3) 49.0 (10.0-145.3) 48.0 (21.9-90.0)

PSA density
 Mean ± SD 0.10±0.06 0.09 ± 0.06 0.12 ± 0.06 <0.0001
 Median (Range) 0.08 (0.02-0.39) 0.07 (0.02-0.39) 0.12 (0.04-0.32)

%fPSA
 Mean ± SD 20.68 ± 7.91 22.26 ± 8.03 18.08 ± 7.03 0.0016
 Median (Range) 19.45 (5.65-41.49) 21.12 (7.92-41.49) 17.52 (5.65-36.71)

%[-2]proPSA
 Mean ± SD 1.54 ± 0.54 1.49 ± 0.43 1.63 ± 0.69 0.3587
 Median (Range) 1.48 (0.45-4.54) 1.48 (0.52-2.64) 1.48 (0.45-4.54)

[-2]proPSA/%fPSA
 Mean ± SD 0.72±0.48 0.60±0.39 0.90±0.55 0.0001
 Median (Range) 0.62 (0.07-2.81) 0.52 (0.07-2.18) 0.76 (0.26-2.81)

phi
 Mean ± SD 31.56±14.42 27.99±10.07 37.45±18.21 0.0002
 Median (Range) 29.08 (10.55-104.62) 26.87 (10.55-64.77) 32.23 (11.14-104.62)

Number of biomarker measurements
Mean ± SD 3.32±1.54 3.47±1.51 3.11±1.57 0.067
Median (Range) 3.0 (2-10) 3.0 (2-10) 3.0 (2-8)

Time from prostate cancer diagnosis to 1st [-2]proPSA (yr)
 Mean ± SD 1.27±0.95 1.39±0.92 1.07±0.97 0.001
 Median (Range) 1.12 (-0.1-5.91) 1.28 (-0.04-5.91) 0.98 (-0.1-5.14)

Time from prostate cancer diagnosis to biopsy reclassification or censoring (yr)
 Mean ± SD 4.43±2.10 4.81±1.93 3.81±2.23 0.0004
 Median (Range) 4.30 (0.96-10.47) 4.78 (1.00-10.00) 3.41 (0.96-10.47)