Figure 4. Supervised cluster analysis with patients sorted according to the presence or absence of ANA associated rheumatic disease (AARD) was performed with antibodies to extractable nuclear antigens (ENA), chromatin, ribosomal P and to DFS70.

ENA, Ro52/TRIM21, SS-A/Ro60 and SS-B/La cluster most closely with AARD whereas DFS70 antibodies and Jo-1 demonstrate high distance clustering.