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. 2014 Apr 4;9(4):e93604. doi: 10.1371/journal.pone.0093604

Table 6. Mtb:ΔRv2745c (comp) 60 min post-diamide treatment.

Function MT # Symbol Description Rv# M1 M2 M3 Average M Value Expression Fold Change
Heat Shock MT0397 clpB ATP-dependent Clp protease, ATP-binding subunit Rv0384c 2.454 1.961 2.321 2.245 4.741
MT3526 groEL1 Rv3417c 1.697 1.664 1.765 1.709 3.269
MT0265 hsp heat shock protein, HSP20 family Rv0251c 2.973 2.698 3.026 2.899 7.459
MT0589 htpX heat shock protein HtpX Rv0563 1.759 1.651 1.804 1.738 3.336
MT0365 dnaK dnaK protein Rv0350 2.158 2.336 3.394 2.629 6.187
MT0367 dnaJ1 dnaJ protein Rv0352 2.377 2.301 3.632 2.770 6.821
Transcription MT2783 sigB RNA polymerase principal sigma factor SigB Rv2710 1.894 1.589 2.014 1.832 3.560
MT1259 sigE RNA polymerase sigma-70 factor, ECF subfamily Rv1221 2.737 2.447 3.679 2.954 7.750
MT3320 sigH RNA polymerase sigma-70 factor, ECF subfamily Rv3223c 3.223 3.345 4.739 3.769 13.635
MT1960 furA Rv1909c 2.465 2.646 2.811 2.641 6.236
MT1009 mprA Rv0981 −1.426 −1.742 −1.638 −1.602 −3.035
MT1260 rseA hypothetical protein Rv1222 2.657 2.646 3.716 3.006 8.034
MT3316 sensor histidine kinase Rv3220c 2.100 1.708 2.563 2.124 4.358
Transport MT2468 cysA1 Rv2397c 3.588 3.563 3.985 3.712 13.107
MT2469 cysW sulfate ABC transporter, permease protein Rv2398c 1.845 1.869 1.635 1.783 3.442
MT1519 Rv1473 3.022 2.958 3.803 3.261 9.588
MT2471 subI sulfate ABC transporter, sulfate−binding Rv2400c 1.098 1.467 1.011 1.192 2.285
Detoxification MT2719 cadI Rv2641 4.175 4.322 6.555 5.017 32.389
MT1517 trxB1 thioredoxin Rv1471 3.349 3.605 5.726 4.227 18.725
MT4032 trxB2 thioredoxin reductase Rv3913 3.218 3.290 5.195 3.901 14.936
MT4033 trxC thioredoxin Rv3914 2.160 2.018 3.730 2.636 6.216
MT1959 katG catalase−peroxidase Rv1908c 1.713 2.331 2.757 2.267 4.814
Lipid metabolism MT0882 fadA Rv0859 −2.372 −1.416 −1.240 −1.676 −3.195
Molybdopterin biosynthesis MT2528 mobA molybdopterin−guanine dinucleotide biosynthesis Rv2453c 2.375 2.000 2.914 2.430 5.388
MT3301 moeB1 HesA/MoeB/ThiF family protein Rv3206c 2.481 2.625 3.363 2.823 7.075
Sulfate metabolism MT1377 cysM cysteine synthase Rv1336 2.346 2.104 2.969 2.473 5.552
MT1324 cysN sulfate adenylate transferase, subunit 1 Rv1286 3.611 3.698 3.389 3.566 11.841
MT1376.1 cysO conserved hypothetical protein Rv1335 2.797 2.808 4.142 3.249 9.507
MT0837 cysA2 thiosulfate sulfurtransferase Rv0815c 1.008 1.467 1.478 1.318 2.493
MT3199 cysA3 thiosulfate sulfurtransferase Rv3117 1.516 1.358 1.686 1.520 2.868
MT2462 cysH phosphoadenosine phosphosulfate reductase Rv2392 1.108 1.405 1.696 1.403 2.645
Intermediary metabolism MT3949 bfrB Rv3841 −1.440 −1.332 −1.177 −1.316 −2.490
MT3969 ethA Rv3854c −1.173 −1.226 −1.200 −2.297
Cell wall associated MT0870 lpqS hypothetical protein Rv0847 1.258 1.157 1.404 1.273 2.416
MT1379 murI glutamate racemase Rv1338 3.322 2.855 3.729 3.302 9.863

Genes induced and repressed by functional category at 60 minutes post-diamide treatment in the complemented strain. n = 3. MT # and Rv # denote the CDC1551 and the H37Rv gene IDs, respectively.