Skip to main content
. 2014 Apr 4;9(4):e94010. doi: 10.1371/journal.pone.0094010

Figure 4. Inhibition of inflammatory pathways suppress virus- induced cytokines.

Figure 4

ppBECs were pretreated with IL-13 + IL-4 (clear bars) or not (shaded bars) for 24 hours prior to infection with RV16 (n = 8). Inhibitors were added 30 minutes prior to infection. Protein secretion in cell supernatant was measured using ELISA (R&D). Statistical analysis used ANOVA (*p<0.05) followed by 4A) IL-8, Wilcoxon (absence) or T-test (presence) of Th2 cytokines, 4B IP-10 Wilcoxon (absence) or T-test (presence) of Th2 cytokines and 4C) GM-CSF, T-test. Data were normalized relative to no treatment and cytokine only controls. Total inhibition is shown as 100% and no inhibition as <1%.