Table 1.
Demographic and clinical characteristics of BE cases and the two control groups
| BE cases (n=173) | Colonoscopy controls (n=343) | Endoscopy controls (n=172) | |||
|---|---|---|---|---|---|
| n (%) | n (%) | p Value | n (%) | p Value | |
| Age, mean SD | 63.1 (7.2) | 62.9 (6.9) | 0.91 | 63.1 (7.3) | 0.88 |
| Sex, men | 170 (98) | 334 (97) | 0.53 | 160 (93) | 0.02 |
| Race | <0.001 | <0.001 | |||
| White | 152 (88) | 194 (57) | 115 (67) | ||
| African American | 18 (10) | 142 (41) | 52 (30) | ||
| Other | 3 (2) | 7 (2) | 5 (3) | ||
| GERD duration | |||||
| No GERD | 61 (36) | 245 (74) | <0.001 | 68 (41) | 0.55 |
| <5 years | 17 (10) | 14 (4) | 20 (12) | ||
| 5–<10 years | 12 (7) | 18 (5) | 14 (8) | ||
| ≥10 years | 79 (47) | 56 (17) | 65 (34) | ||
| PPI use | 119 (72) | 72 (22) | <0.001 | 98 (60) | 0.01 |
| NSAID intake | 84 (50) | 171 (52) | 0.85 | 80 (49) | 0.74 |
| Tobacco smoking | |||||
| <1 pack-year | 35 (22) | 97 (29) | 0.06 | 57 (35) | 0.02 |
| 1–30 pack-years | 57 (36) | 125 (38) | 57 (35) | ||
| ≥30 pack-years | 68 (42) | 107 (33) | 50 (30) | ||
| Alcohol drinking | |||||
| Never | 12 (7) | 23 (7) | 0.46 | 12 (7) | 0.69 |
| Former | 85 (52) | 189 (57) | 77 (47) | ||
| Current | 68 (41) | 118 (36) | 75 (46) | ||
| BMI | |||||
| Mean | 30.3 (5.0) | 31.4 (6.1) | 0.05 | 30.5 (7.1) | 0.76 |
| <25 | 24 (14) | 42 (12) | 0.79 | 36 (21) | 0.17 |
| 25–30 | 63 (36) | 121 (35) | 52 (30) | ||
| >30 | 86 (50) | 180 (53) | 84 (49) | ||
| Helicobacter pylori | 32 (19) | 120 (36) | <0.001 | 51 (30) | 0.02 |
BE, Barrett’s oesophagus; BMI, Body mass index; NSAID, non-steroidal anti-inflammatory drug; PPI, proton pump inhibitors.