Table 4.
The distribution of abdominal fat measured by CT scan among BE cases and the colonoscopy control group
| BE<3 cm (n=104) | BE≥3 cm (n=69) | |||||
|---|---|---|---|---|---|---|
| n (%) | Unadjusted OR for BE<3 cm vs no BE | Adjusted* OR for BE<3 cm (no GERD or PPI) | n (%) | Unadjusted OR for BE≥3 cm vs no BE | Adjusted* OR for BE≥3 cm (no GERD or PPI) | |
| VAT (cm2) | ||||||
| Median | 171.1 | 182.7 | ||||
| 1st tertile (<142.9) | 29 (28) | 1.0 | 1.0 | 12 (17) | 1.0 | 1.0 |
| 2nd tertile (142.9–<226.0) | 37 (36) | 1.43 (0.83 to 2.48) | 1.30 (0.71 to 2.39) | 28 (41) | 2.62 (1.27 to 5.39) | 1.98 (0.93 to 4.21) |
| 3rd tertile (≥226.0) | 38 (36) | 1.66 (0.96 to 2.88) | 1.20 (0.65 to 2.22) | 29 (42) | 3.06 (1.49 to 6.30) | 1.76 (0.83 to 3.74) |
| p Trend | 0.07 | 0.001 | ||||
| SAT (cm2) | ||||||
| Median | 269.0 | 314.6 | ||||
| 1st tertile (<246.9) | 31 (30) | 1.0 | 1.0 | 24 (35) | 1.0 | 1.0 |
| 2nd tertile (246.9–<360.2) | 51 (49) | 1.74 (1.03 to 2.92) | 1.99 (1.12 to 3.51) | 22 (32) | 0.97 (0.51 to 1.83) | 0.96 (0.48 to 1.92) |
| 3rd tertile (≥360.2) | 22 (21) | 0.64 (0.35 to 1.16) | 0.71 (0.37 to 1.36) | 23 (33) | 0.86 (0.46 to 1.61) | 0.94 (0.48 to 1.82) |
| p Trend | 0.13 | 0.63 | ||||
| VAT to SAT ratio | ||||||
| Median | 0.64 | 0.68 | ||||
| 1st tertile (<0.47) | 27 (26) | 1.0 | 1.0 | 12 (17) | 1.0 | 1.0 |
| 2nd tertile (0.47–<0.76) | 38 (36) | 1.70 (0.98 to 2.96) | 1.63 (0.98 to 2.68) | 27 (39) | 2.72 (1.32 to 5.61) | 2.19 (1.03 to 4.68) |
| 3rd tertile (≥0.76) | 39 (38) | 1.98 (1.13 to 3.44) | 1.47 (0.88 to 2.45) | 30 (44) | 3.42 (1.67 to 7.01) | 1.93 (0.92 to 4.09) |
| p Trend | 0.01 | <0.001 | ||||
BE cases categorised by length of BE segment as <3 and ≥3 cm.
*
Adjusted for age, gender, race, NSAID, Helicobacter pylori infection, smoking and alcohol.
BE, Barrett’s oesophagus; NSAID, non-steroidal anti-inflammatory drug; PPI, proton pump inhibitors; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.