Figure 1.

(a) Setup and the detailed channel dimensions of the cell culture device used in the present study. (b) Simulated temporal evolution of the concentration along the thin channel after the injection of a 0.1 μM EGF into one of the thick channels at a flow rate of 100 μl/h. (c) Simulated EF strengths inside the channel with a driving current of 2.76 μA. Top, side view; bottom, bottom view of the channels. Because of the large difference in the channel cross section from the thick to the thin channel, most of the voltage drop and hence the EF occurs in the thin channel.