Table 2.
Clinical characteristics of patients with benign disease-associated HLH
| Case | Splenomegaly | Hemophagocytosis (bone marrow) | NCC (/μl) | Histiocyte (%) | HLH-2004 | sIL2R (U/ml) | Ferritin (ng/ml) | sIL2R/ferritin |
|---|---|---|---|---|---|---|---|---|
| B1 | + | + | 65.0 × 104 | 0.6 | 5 (8) | 2,162 | 26,798 | 0.08 |
| B2 | + | + | 3.0 × 104 | 1.6 | 5 (8) | 2,704 | 11,775 | 0.22 |
| B3 | + | + | 8.6 × 104 | 6.0 | 5 (8) | 8,657 | 29,577 | 0.29 |
| B4 | + | + | 7.0 × 104 | 2.6 | 5 (8) | 3,660 | 11,174 | 0.32 |
| B5 | + | + | 2.1 × 104 | 9.6 | 7 (8) | 4,028 | 6,865 | 0.58 |
| B6 | + | + | 3.0 × 104 | 1.0 | 5 (8) | 2,416 | 882 | 2.73 |
| B7 | + | n.t. | n.t. | n.t. | 5 (8) | 2,563 | 6,947 | 0.37 |
| B8 | + | n.t. | n.t. | n.t. | 5 (8) | 3,222 | 2,746 | 1.17 |
| B9 | + | + | 0.9 × 104 | 3.0 | 5 (8) | 6,078 | 7,852 | 0.77 |
| B10 | + | + | 6.0 × 104 | 3.4 | 5 (8) | 6,271 | 100,000 | 0.06 |
NCC nuclear cell count, n.t. not tested