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. 2013 Oct 25;93(5):821–826. doi: 10.1007/s00277-013-1925-8

Table 5.

Comparison of the laboratory findings of the two groups (benign disease-associated HLH and LAHS)

Benign disease-associated HLH Range LAHS Range p value
Mean ± SD Mean ± SD
n = 10 n = 11
WBC (×109/l) 4,050 ± 1,152 600–13,800 4,509 ± 799 1,800–10,700 NS
ANC (×109/l) 2,440 ± 1,170 189–12,765 3,119 ± 650 1,026–7,875 <0.05
Hb (g/dl) 11.8 ± 0.5 9.2–13.8 9.4 ± 0.5 7.4–12.6 <0.01
PLT (×109/l) 7.2 ± 1.1 4.2–13.9 10.8 ± 1.4 5.0–20.5 <0.05
AST (U/l) 1,161 ± 622 40–6,300 63.4 ± 14.2 20–157 <0.01
ALT (U/l) 904 ± 391 37–3,400 36.3 ± 10.9 8–132 <0.001
LDH (/UNL) 8.1 ± 3.2 1.4–32.3 3.6 ± 0.7 1.3–8.9 NS
CRP (mg/dl) 9.4 ± 2.9 0.4–23.6 9.0 ± 2.6 0.3–29.3 NS
sIL-2R (U/ml) 4,176 ± 677 2,162–8,657 13,451 ± 3,611 3,462–36,938 <0.005
Ferritin (ng/ml) 20,462 ± 9,330 882–100,000 2,561 ± 544 619–6,067 <0.005
sIL-2R/ferritin 0.66 ± 0.25 0.06–2.73 8.56 ± 2.79 0.72–31.1 <0.0005

UNL upper normal limit, NS not significant