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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Hypertens. 2014 Jan;32(1):154–165. doi: 10.1097/HJH.0b013e3283658a53

FIGURE 3.

FIGURE 3

(a) Representative three-dimensional computed tomography (CT) image of the left ventricle (left) demonstrating schematically sampling for myocardial micro-CT analysis (white box) and subsequent three-dimensional micro-CT reconstruction of myocardial microvascular architecture (right). Quantification of spatial density of microvessels in the subepicardium (b) and subendocardium (c). (d) Myocardial vessel wall-to-lumen ratio and its quantification in α-smooth muscle actin stained slides (40×). (e) In-situ production of superoxide anion with dihydroethidium (DHE). (f) Myocardial expression of the NADPH-oxidase subunits p47 and p67, and nitrotyrosine. *P ≤0.05 vs. normal; P <0.05 vs. RVHT +PTRS +Bendavia. PTRS, percutaneous transluminal renal angioplasty and stenting; RVHT, renovascular hypertension.